Tag

chromosomal insertions

19
Nov

Balanced chromosomal insertions microstructural abnormalities

Chromosomal insertions often cause structural abnormalities that result in an overt phenotype and symptoms. However, those who carry balanced insertions can be asymptomatic when disease-causing genes are not disrupted. While the individual may not be affected, the balanced insertion could serve as an underlying mechanism for recurrent familial microstructural abnormalities...
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